Together we are
moving medicine forward.
Who we are: A timeline
SBRG is a medical research and services company created by physicians for physicians to improve health and human potential.
Historic Events
Dr. Duraffourd and Dr. Lapraz begin collaboration in developing and teaching Endobiogeny
Endobiogeny in official use in oncology, Boucicaut Hospital, Paris
Drs. Lapraz and Hedayat begin collaboration in evolving Endobiogeny training
SBRG co-founded by Drs. Lapraz and Hedayat
Daniel Henry, former head Merck Chemical division named CEO, oversees clinical services and first fundraising
Jeremy Rigby named CEO, brings clinical research trials experience, leads global commercialization of products and services
Developments and Teachings in Endobiogeny
Seminars in Clinical Phytotherapy, a re-conception of herbal medicine personalized to physiology as opposed to symptoms
Seminars in Neuroendocrine theory of terrain, precursor of Endobiogeny
Official presentation of the Theory of Endobiogeny
International training in Endobiogeny
Development of Global Living Systems Theory: scientific formalization and expansion of Endobiogeny
Jeremy Rigby named CEO, brings clinical research trials experience, leads global commercialization of products and services
Research, Discoveries, and Patents
1st biological modeling indexes by Dr. Duraffourd
1st biological modeling indexes by Dr. Hedayat, 1st to model neuro-metabolic determinates of perception and emotional reactivity
1st patent granted: US-9953139-B2
1st predictive algorithm: risk of mortality post myocardial infarction
2nd predictive algorithm: risk of mortality in hospitalized patients with COVID-19
GEMMA 1.0 biological modeling system, introduction of GEMMA Panels
Publications
1st Publication:Phytothérapie: Une Médecine Nouvelle (Ed. Presses de la Renaissance)
1st Endobiogeny Book: Traité de Phytothérapie Clinique (Ed. Masson)
2013: 1st Peer-Reviewed Article: Endobiogeny: A global Approach to Systems Biology (part 1 of 2)
1st University-Based Clinical Study: A Novel Use of Biomarkers in the Modeling of Cancer Activity Based on the Theory of Endobiogeny
1st Textbook on Endobiogeny: The Theory of Endobiogeny, volumes 1-4, Academic Press
2025: 1st Publication Under Global Living Systems Theory: Chp. 22: From Systems Thinking to P4 Medicine, in Systems Biology and In-Depth Applications for Unlocking Diseases, Ed. B. Sokouti, Elsevier Press
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Historic Events
02
Developments and Teachings in Endobiogeny
03
Research, Discoveries and Patents
04
Publications
Historic Events
Dr. Duraffourd and Dr. Lapraz begin collaboration in developing and teaching Endobiogeny
Endobiogeny in official use in oncology, Boucicaut Hospital, Paris
Drs. Lapraz and Hedayat begin collaboration in evolving Endobiogeny training
SBRG co-founded by Drs. Lapraz and Hedayat
Daniel Henry, former head Merck Chemical division named CEO, oversees clinical services and first fundraising
Jeremy Rigby named CEO, brings clinical research trials experience, leads global commercialization of products and services
Our Co-Founders
Dr Lapraz is responsible for international promotion and official recognition of Endobiogeny. He serves as resource and reference for the continuity of Endobiogeny from Dr. Duraffourd to Dr. Hedayat.
Trained by Dr. Lapraz, Dr. Hedayat specializes in clinical research, clinical solutions and publication. He is chief architect of GEMMA, developer of over 200 indexes and panels, and lead author on over a 20 articles, chapters and textbooks in integrative physiology, critical care and comparative medical ethics.
What we do
SBRG aims to become the premier global medical
diagnostic-informatics company, leveraging the intersection
of clinical and environmental data with proprietary
biomarker analysis.
We specialize in the development of commercial products for
medical decision-making and clinical solutions for physicians.
Frequently asked questions about SBRG
Is Endobiogeny alternative medicine?
No. It’s an advancement on the current biomedical model of health and disease by applying systems theory and the principles of integrative physiology. Endobiogeny promotes rational, evidenced-based standards of care. Where none are available, Endobiogeny offers insights by addressing underlying imbalances, which renders the “untreatable” treatable.
Does SBRG collaborate with other entities for research and/or product development initiatives?
Yes. SBRG is open to collaborative research and product development partnerships for both academic and commercial endeavors.
For inquiries, please email khedayat@systemsbrg.com
Can SBRG intellectual property be licensed for research and/or commercialization?
Yes. For inquiries, please email jrigby@systemsbrg.com
Does SBRG accept investors?
Yes. SBRG is a privately funded company that accepts individual and institutional investors. For inquiries, please email jrigby@systemsbrg.com
